Journal
/
/
通过结合70%部分切除术和对乙酰氨基酚,生成急性肝衰竭大鼠模型
JoVE Journal
Medicine
Author Produced
A subscription to JoVE is required to view this content.  Sign in or start your free trial.
JoVE Journal Medicine
Generation of a Rat Model of Acute Liver Failure by Combining 70% Partial Hepatectomy and Acetaminophen
DOI:

09:44 min

November 27, 2019

, , , , , , , , , ,

Chapters

  • 00:00Title
  • 01:54Procedure
  • 02:13Pre-operative Procedures
  • 03:12Partial Hepatectomy to Remove 70% Liver Mass
  • 05:38Post-operative Care
  • 06:35Injection of Drug in Partially Hepatectomized Animals to induce Liver Failure
  • 06:58Results
  • 09:19Conclusion

Summary

Automatic Translation

本研究开发的急性肝衰竭动物模型为研究潜在疗法提供了可行的替代方法。目前的模型采用身体和药物引起的肝损伤的综合效应,为研究新疗法的潜力提供了一个合适的时间窗口。

Related Videos

Read Article