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Journal / Neuroscience / 高通量图像引导立体定向神经导航和聚焦超声系统，用于在啮齿动物中打开血脑屏障…
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Neuroscience

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JoVE Journal Neuroscience
高通量图像引导立体定向神经导航和聚焦超声系统，用于在啮齿动物中打开血脑屏障
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高通量图像引导立体定向神经导航和聚焦超声系统，用于在啮齿动物中打开血脑屏障

Article DOI: 10.3791/61269-v • 08:02 min • July 16th, 2020
July 16th, 2020 •
*1,2, *2, 2, 3, 1,2, 2, 1,2, 1,2, 3
1Amsterdam UMC, Vrije Universiteit Amsterdam, Pediatric Oncology, Cancer Center Amsterdam, 2Princess Máxima Center for Pediatric Oncology, 3Imaging Division, Utrecht University
* These authors contributed equally

Summary
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血脑屏障 （BBB） 可以通过微泡介导的聚焦超声波 （FUS） 暂时中断。在这里，我们描述了一个逐步协议的高通量BBB打开体内使用模块化FUS系统，为非超声专家访问。

Tags

神经科学，第161期，高通量工作流程，聚焦超声波，药物输送，图像引导的造音，血脑屏障
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