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Journal / Immunology and Infection / Estabilidade e Estrutura do Complexo de…
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Immunology and Infection

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JoVE Journal Immunology and Infection
Estabilidade e Estrutura do Complexo de Histocompatibilidade Maior do Morcego Classe I com β Heterologous2-Microglobulina
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Estabilidade e Estrutura do Complexo de Histocompatibilidade Maior do Morcego Classe I com β Heterologous2-Microglobulina

Article DOI: 10.3791/61462-v • 11:17 min • March 10th, 2021
March 10th, 2021 •
*1,2, *3,4, *2,5, 1,2, 1,2, 2, 2, 4, 1, 4, 1,2
1School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, 2NHC Key Laboratory of Biosafety, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, 3Faculty of Health Sciences, University of Macau, 4CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, 5Savaid Medical School, University of Chinese Academy of Sciences
* These authors contributed equally

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O protocolo descreve métodos experimentais para obter substituições estáveis do complexo de histocompatibilidade principal (MHC) classe I através de substituições potenciais β 2-microglobulina (β2m) de diferentes espécies. A comparação estrutural do MHC I estabilizada por homólogos e heteromaníacos β2m foram investigadas.

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Imunologia e Infecção Questão 169 Maior histocompatibilidade antígeno complexo (MHC) moléculas classe I β estrutura complexa de 2-microglobulina (β2m) peptídeo TCR tetramer
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