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Medicine
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Acute Kidney Injury Model Induced by Cisplatin in Adult Zebrafish
 

Acute Kidney Injury Model Induced by Cisplatin in Adult Zebrafish

Article DOI: 10.3791/61575
May 15th, 2021

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Summary May 15th, 2021

This protocol describes the procedures to induce Acute Kidney Injury (AKI) in adult zebrafish using cisplatin as a nephrotoxic agent. We detailed the steps to evaluate the reproducibility of the technique and two techniques to analyze inflammation and cell death in the renal tissue, flow cytometry and TUNEL, respectively.

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