Journal
/
Medicine
/
Assessing Teratogenic Changes in a Zebrafish Model of Fetal Alcohol Exposure
JoVE Journal
Medicine
This content is Free Access.
JoVE Journal Medicine
Assessing Teratogenic Changes in a Zebrafish Model of Fetal Alcohol Exposure

Assessing Teratogenic Changes in a Zebrafish Model of Fetal Alcohol Exposure

DOI:
10.3791/3704-v

•

10:07 min

•

March 20, 2012

•

,
1Program in Developmental Biology,Children’s Memorial Research Center, 2Department of Pediatrics,Northwestern University

Chapters

  • 00:05Title
  • 01:25Treatment of Embryos with Ethanol and Collection
  • 03:36Assessing Ethanol-induced Gene Expression Changes and Developmental Consequences
  • 05:40Manipulating the Zebrafish Embryo
  • 06:49Representative Zebrafish Ethanol-exposure Results
  • 09:40Conclusion

Summary

Automatic Translation

Automatic Translation

In order to understand the molecular mechanisms of the ethanol-induced developmental damage, we have developed a zebrafish model of ethanol exposure and are exploring the physical, cellular, and genetic alterations that occur after ethanol exposure1. We then seek to find potential interventions and rapidly test them in this animal model.

Tags

Teratogenic ChangesZebrafish ModelFetal Alcohol ExposureFetal Alcohol Syndrome (FAS)Fetal Alcohol Spectrum Disorder (FASD)Maternal Alcohol ConsumptionDevelopmental Ethanol ExposureZebrafish EmbryoTeratogen StudyGross Developmental DefectsZebrafish FAS Model

Article

Embed

ADD TO PLAYLIST

Usage Statistics

Related Videos

check_url/3704?article_type=v

The Polyvinyl Alcohol Sponge Model Implantation
check_url/3704?article_type=v

A Novel Surgical Approach for Intratracheal Administration of Bioactive Agents in a Fetal Mouse Model
check_url/3704?article_type=v

Screening for Melanoma Modifiers using a Zebrafish Autochthonous Tumor Model
check_url/3704?article_type=v

Fetal Echocardiography and Pulsed-wave Doppler Ultrasound in a Rabbit Model of Intrauterine Growth Restriction
check_url/3704?article_type=v

Assessing Changes in Volatile General Anesthetic Sensitivity of Mice after Local or Systemic Pharmacological Intervention
check_url/3704?article_type=v

A Possible Zebrafish Model of Polycystic Kidney Disease: Knockdown of wnt5a Causes Cysts in Zebrafish Kidneys
check_url/3704?article_type=v

A Mouse Fetal Skin Model of Scarless Wound Repair
check_url/3704?article_type=v

Generation of a Chronic Obstructive Pulmonary Disease Model in Mice by Repeated Ozone Exposure
check_url/3704?article_type=v

Construction and Evaluation of a Murine Calvarial Osteolysis Model by Exposure to CoCrMo Particles in Aseptic Loosening
check_url/3704?article_type=v

Model Surgical Training: Skills Acquisition in Fetoscopic Laser Photocoagulation of Monochorionic Diamniotic Twin Placenta Using Realistic Simulators

Read Article