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Journal / Cancer Research / Un modelo de xenoinjerto murino de Ommaya para…
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Cancer Research

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JoVE Journal Cancer Research
Un modelo de xenoinjerto murino de Ommaya para estudiar la terapia dirigida directamente de la enfermedad leptomeningeal
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Un modelo de xenoinjerto murino de Ommaya para estudiar la terapia dirigida directamente de la enfermedad leptomeningeal

Article DOI: 10.3791/62033-v • 07:17 min • January 29th, 2021
January 29th, 2021 •
1,2, 3, 4, 4, 1, 5, 6, 7, 4, 2, 1,2
1Department of Neuro-Oncology, H. Lee Moffitt Cancer Center & Research Institute, 2Department of Tumor Biology, H. Lee Moffitt Cancer Center & Research Institute, 3Department of Comparative Medicine, University of South Florida, 4Department of Breast Oncology, H. Lee Moffitt Cancer Center & Research Institute, 5Department of Cancer Physiology, H. Lee Moffitt Cancer Center & Research Institute, 6Department of Drug Discovery, H. Lee Moffitt Cancer Center & Research Institute, 7Department of Medical Oncology, Roswell Park Comprehensive Cancer Center

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Aquí, describimos un modelo de xenoinjerto murino que se asemeja funcionalmente a un reservorio de Ommaya en pacientes. Desarrollamos el Ommaya murino para estudiar nuevas terapias para la enfermedad leptomeningeal universalmente fatal.

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Cancer Research Número 167 Enfermedad leptomeningeal modelos experimentales modelo murino reservorio murino de Ommaya
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