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Journal / Cancer Research / Co-kultur af Glioblastoma Stamceller på mønstrede …
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Cancer Research

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JoVE Journal Cancer Research
Co-kultur af Glioblastoma Stamceller på mønstrede neuroner til at studere migration og cellulære interaktioner
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Co-kultur af Glioblastoma Stamceller på mønstrede neuroner til at studere migration og cellulære interaktioner

Article DOI: 10.3791/62213-v • 10:08 min • February 24th, 2021
February 24th, 2021 •
1, 2,3, 4, 1, *2, *4
1University Bordeaux, INSERM, LAMC, U1029, 33600, Pessac, France, 2Univ. Bordeaux, CNRS, Interdisciplinary Institute for Neuroscience, IINS, UMR 5297, Bordeaux, France, 3Alvéole, Bordeaux, France, 4University Bordeaux, CNRS, IBGC, UMR5095, 33000, Bordeaux, France
* These authors contributed equally

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Her præsenterer vi en brugervenlig co-kulturanalyse til at analysere glioblastoma (GBM) migration på mønstrede neuroner. Vi udviklede en makro i FiJi-software for nem kvantificering af GBM-cellemigration på neuroner og observerede, at neuroner ændrer GBM-celle invasiv kapacitet.

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Kræftforskning Problem 168 glioblastoma patient-afledt celle sfæroid invasion neuroner avancerede in vitro modeller
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