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通过在小鼠心脏中应用光遗传学多位点光刺激进行高级心律管理
JoVE Journal
Medicine
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JoVE Journal Medicine
Advanced Cardiac Rhythm Management by Applying Optogenetic Multi-Site Photostimulation in Murine Hearts
DOI:

08:43 min

August 26, 2021

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Chapters

  • 00:04Introduction
  • 00:54Langendorff Perfusion
  • 02:53Arrhythmia Induction and Optical Defibrillation
  • 04:41Optical Mapping
  • 05:45Results: Analysis of Success Rates and Manipulation of Cardiac Rhythm by Means of Photosimulation
  • 07:56Conclusion

Summary

Automatic Translation

这项工作报告了一种使用micro-LED阵列的局部光刺激和同时光学映射心外膜电位来控制转基因通道视紫红质-2(ChR2)小鼠完整鼠心脏心律的方法。

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