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合并的shRNA文库筛选,以确定调节耐药性表型的因素
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Article
DOI:
10.3791/63383-v
•
14:51 min
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June 17th, 2022
合并的shRNA文库筛选,以确定调节耐药性表型的因素
June 17th, 2022
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Saswati Das1,2, Raveen Stephen Stallon Illangeswaran1,2, Smitha Ijee2,3, Sanjay Kumar2,3, Shaji Ramachandran Velayudhan1,2,3, Poonkuzhali Balasubramanian1,2,3
Chapters
Summary
Please note that all translations are automatically generated.
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使用慢病毒 shRNA 池的高通量 RNA 干扰 (RNAi) 筛选可以成为检测恶性肿瘤中治疗相关合成致死靶标的工具。我们提供一种合并的shRNA筛选方法来研究急性髓系白血病(AML)中的表观遗传效应子。