Login processing...

Trial ends in Request Full Access Tell Your Colleague About Jove
JoVE Journal
Cancer Research

A subscription to JoVE is required to view this content.

Positron Emission Tomography Imaging of Cell Trafficking

Positron Emission Tomography Imaging of Cell Trafficking: A Method of Cell Radiolabeling

Article DOI: 10.3791/64117-v 10:07 min October 27th, 2023
October 27th, 2023



Presented here is a protocol to radiolabel cells with a positron emission tomography (PET) radioisotope, 89Zr (t1/2 78.4 h), using a ready-to-use radiolabeling synthon, [89Zr]Zr-p-isothiocyanatobenzyl-desferrioxamine ([89Zr]Zr-DBN). Radiolabeling cells with [89Zr]Zr-DBN allows noninvasive tracking and imaging of administered radiolabeled cells in the body with PET for up to 7 days post-administration.


Positron Emission Tomography Cell Trafficking Radiolabeling Zirconium-89-DBN PET Imaging Cell Therapies Neurological Diseases Cancers Pharmacokinetics Hydroxamate Resin Anhydrous Acetonitrile Hydrochloric Acid
Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
Simple Hit Counter