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Developmental Biology

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Development of Organoids from Mouse Pituitary as In Vitro Model to Explore Pituitary Stem Cell Biology
 

Development of Organoids from Mouse Pituitary as In Vitro Model to Explore Pituitary Stem Cell Biology

Article DOI: 10.3791/63431-v 09:48 min February 25th, 2022
February 25th, 2022

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Summary

The pituitary gland is the key regulator of the body's endocrine system. This article describes the development of organoids from the mouse pituitary as a novel 3D in vitro model to study the gland's stem cell population of which the biology and function remain poorly understood.

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Organoids Mouse Pituitary In Vitro Model Pituitary Stem Cell Biology Homeostasis Pituitary Remodeling Neonatal Maturation Aging-associated Functional Decline Tumor Growth Primary Mouse Pituitary Stem Cells Emma Laporte Charlotte Nys PhD Students Mouse Head Deionized Water Sterile Environment Surgical Tools Cranium Nose Bridge Tweezers Pituitary Gland Diaphragma Sellae Stereomicroscope Anterior Lobe Posterior Lobe Intermediate Lobe Erlenmeyer Flask Medium A Trypsin Solution DNAse Solution
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