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在计算机中 心血管疾病的临床试验
JoVE Journal
Bioengineering
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JoVE Journal Bioengineering
In Silico Clinical Trials for Cardiovascular Disease
DOI:

09:09 min

May 27, 2022

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Chapters

  • 00:04Introduction
  • 01:30Workflow for Ultrasound M‐Mode or Apical View DICOM Image Analysis and LV Parameter Extraction
  • 02:34PAK Finite Element Solver for Fluid‐Structure (FS) Simulations
  • 04:30Determination of Ventricular Activation Sequence from ECG Measurement
  • 06:27Results: Fibers Direction, Velocity, Pressure Field, and Displacements in the Parametrical LV Model, Simulation of Whole‐Heart Activation, and Maps of Body Surface Potential
  • 08:17Conclusion

Summary

Automatic Translation

该协议演示了 SILICOFCM 平台的工作流程,通过应用心脏的多尺度机电模型,从患者特定的超声图像自动生成左心室的参数模型。该平台支持 计算机临床试验, 旨在减少实际临床试验并最大限度地提高积极的治疗效果。

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