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Optical Trapping of Plasmonic Nanoparticles for In Situ Surface-Enhanced Raman Spectroscopy Characterizations
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Chapters
- 00:04Introduction
- 01:00Optical Setup
- 01:47Preparation of Sample Chamber and Generation of AgNp Assembly for SERS Measurement
- 04:13Results: SERS Spectra of the Analyte Molecules Enhanced by the Plasmonic AgNp Assembly
- 05:32Conclusion
The present protocol describes a convenient approach to integrating optical trapping and surface-enhanced Raman spectroscopy (SERS) to manipulate plasmonic nanoparticles for sensitive molecular detection. Without aggregating agents, the trapping laser assembles plasmonic nanoparticles to enhance the SERS signals of target analytes for in situ spectroscopic measurements.
Tags
Keywords: Optical TrappingPlasmonic NanoparticlesSurface-enhanced Raman SpectroscopySERS-active Nanoparticle AssemblyAnalyte DetectionBiomarker DetectionMicrofluidic System532-nanometer LaserLiquid-nitrogen-cooled Charge-coupled Device CameraSilver NanoparticlesDSNB SolutionRaman Excitation Source Laser
