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Induksjon og ulike vurderingsindikatorer for eksperimentell autoimmun encefalopati
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Induksjon og ulike vurderingsindikatorer for eksperimentell autoimmun encefalopati

Article DOI: 10.3791/63866-v • 06:19 min • September 9th, 2022
September 9th, 2022 •
*1, *1, 1,2, 1, 1, 1, 1, 1, 1, 1, 3, 1
1Putuo People's Hospital, Shanghai Key Laboratory of Signaling and Disease Research, School of Life Sciences and Technology, Tongji University, 2National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, 3Department of Infectious Diseases, Shanghai Key Laboratory of Infectious Diseases and Biosafety Emergency Response, National Medical Center for Infectious Diseases, Huashan Hospital, Fudan University
* These authors contributed equally

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Denne protokollen beskriver induksjon av eksperimentell autoimmun encefalomyelitt i en musemodell ved bruk av myelin oligodendrocyttglykoprotein og overvåking av sykdomsprosessen ved hjelp av et klinisk skåringssystem. Eksperimentelle autoimmune encefalomyelittrelaterte symptomer analyseres ved hjelp av mus femur mikro-computertomografi analyse og åpent felt test for å vurdere sykdomsprosessen omfattende.

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Biologi utgave 187 multippel sklerose eksperimentell autoimmun encefalomyelitt myelin oligodendrocytt glykoprotein nevroinflammasjon angstlignende oppførsel osteoporose
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