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JoVE Journal Bioengineering
Tijd-opgeloste in vivo meting van neuropeptidedynamica door capacitieve immunoprobe in porcine heart
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Tijd-opgeloste in vivo meting van neuropeptidedynamica door capacitieve immunoprobe in porcine heart

Article DOI: 10.3791/63926-v • 08:20 min • May 19th, 2022
May 19th, 2022 •
1, 1, 2,3, 1
1Department of Physiology and Biophysics, Case Western Reserve University, 2University of California Los Angeles (UCLA) Cardiac Arrhythmia Center, David Geffen School of Medicine, 3UCLA Neurocardiology Research Program of Excellence, UCLA

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Gevestigde immunochemische methoden om peptidetransmitters in vivo te meten, vertrouwen op microdialyse of bulkvloeistoftrekking om het monster te verkrijgen voor offline analyse. Deze lijden echter aan spatiotemporale beperkingen. Het huidige protocol beschrijft de fabricage en toepassing van een capacitieve immunoprobe biosensor die de beperkingen van de bestaande technieken overwint.

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Bio-engineering Nummer 183
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