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JoVE Science Education Coronavirus / COVID-19 Procedures
COVID-19 / Coronavirus Outbreak: Protecting The Airway – Endotracheal Intubation

Epidemia da coronavirus / COVID-19: protezione delle vie aeree - intubazione endotracheale

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Overview

In tempi di pandemia, il personale medico sta diventando una risorsa chiave nella lotta contro l’infezione. Per ottenere le migliori cure mediche, le tecniche e le procedure pertinenti devono essere insegnate al personale medico per ridurre il rischio di infezione. I pazienti COVID hanno spesso bisogno di ventilazione meccanica a causa dell’insufficienza respiratoria progrediente, quindi un’intubazione endotracheale diventa una procedura critica nella gestione di questi pazienti. Questa procedura ha un aumentato rischio di infezione a causa della formazione di aerosol e del lavoro con le vie aeree non protette. La sicurezza del paziente non deve essere trascurata e devono essere evitate complicazioni come l’ipossiemia e l’aspirazione. Allo stesso tempo, la protezione personale dalle infezioni è della massima importanza perché le risorse umane in una crisi pandemica devono essere preservate. Questo video mostra la procedura di intubazione endotracheale tenendo conto della protezione dalle infezioni personali.

Procedure

Gli obiettivi chiave di questo protocollo sono la riduzione della formazione di aerosol e l’induzione rapida della sequenza. Ci sono diverse raccomandazioni critiche per questo protocollo: tenere una soglia bassa per l’intubazione precoce, utilizzare la video laringoscopia in prima linea, evitare l’ossigenoterapia ad alto flusso per ridurre la formazione di aerosol, avere il minor numero possibile di personale nella stanza e utilizzare liste di controllo per la preparazione e la procedura. Preparare i materiali necessari al di fuori della stanza del paziente. Offri una panoramica al team. Equipaggiamento protettivo individuale Donn (camice, berretto, occhiali, guanti) e attrezzatura aggiuntiva per lavorare con le vie aeree aperte: maschera FFP3 / N-95, visiera e un secondo paio di guanti. Collegare i doppi filtri al ventilatore e controllare i punti di connessione dei tubi del ventilatore. Informare il paziente sulla procedura in sospeso e ottenere il consenso. Ottenere il monitoraggio emodinamico (ECG, SpO2, NBP). Ottimizzare la posizione del paziente e i requisiti di intubazione elevando la parte superiore del corpo. Testare l’unità di aspirazione. Test di accesso venoso (minimo 2). FERMA l’intero team: segui un principio di 10 secondi per 10 minuti (discutere problemi, opinioni, fatti, piani) e una lista di controllo del processo. Interrompere l’apporto di ossigeno (lasciare la cannula nasale O2 in posizione) e rimuovere la maschera di protezione del paziente. Posizionare la maschera respiratoria e stringerla con entrambe le mani. Avviarel’apporto di ossigeno attraverso la cannula nasale O 2 a 3 litri/min. Iniziare la pre-ossigenazione con FiO2 1.0 con il ventilatore (CPAP senza supporto di pressione, PEEP 5 mbar) per 3-5 minuti. Controllare l’emodinamica e preparare i vasopressori per l’ipotensione. Somministrare rapidamente anestetici e rilassanti muscolari e attendere almeno 45 secondi. Questo viene fatto per ottenere buone condizioni di intubazione e per garantire che il paziente non tossire durante l’intubazione. Interrompere l’apporto di ossigeno attraverso la cannula nasale, quindi arrestare il ventilatore. Rimuovere la maschera respiratoria e posizionarla in modo sicuro accanto al paziente. Eseguire l’intubazione endotracheale utilizzando la video laringoscopia per evitare di avvicinarsi troppo alle vie aeree non protette. Blocca il bracciale non appena il tubo è in posizione. Collegare il ventilatore con l’unità di aspirazione chiusa integrata. Controllare i siti di connessione dei tubi del ventilatore. Avviare il ventilatore. Verificare il corretto posizionamento del tubo con capnografia e auscultazione. Rimuovere la cannula nasale O2 Fissare il tubo endotracheale. Rimuovere un paio di guanti esterni. Inserire il sondino nasogastrico. In caso di vie aeree inaspettatamente difficili, i dispositivi sopraglottici delle vie aeree sono preferiti alla ventilazione della maschera a causa del minor rischio di formazione di aerosol. Tutto il materiale necessario necessario per una via aerea difficile deve essere collocato al di fuori dell’area contaminata e deve essere garantito un rapido accesso a un assistente aggiuntivo.

Disclosures

No conflicts of interest declared.

Transcript

Dearest colleagues. The aims of early intubation in COVID-19 patients with respiratory failure are both to prevent aerosolization of respiratory tract fluids and avoid intubation under emergency conditions.

A low threshold for early intubation of COVID-19 patients should be held and a modified rapid sequence induction with videolaryngoscopic intubation utilized. High-flow or non-invasive ventilation therapy should be avoided, and if not possible, used for the shortest period of time.

Fiber optic intubation should also be avoided due to risk of aerosolization. All necessary equipment for intubation is prepared outside of the patient’s room.

The team should be kept to the minimal number of personnel required to carry out the procedure. Typically, this would consist of one intubating doctor, a doctor with oversight who also manages the cardiovascular system, a nurse or operating department assistant to operate the ventilator, and a second nurse or operating department practitioner to apply the anesthetic agents and supply intubation equipment.

Additionally, there should be a runner assigned to wait outside of the room. In case additional equipment or materials are needed, an intubation checklist, which is tailor-made by every hospital according to their resources will now be carried out by the second doctor and will be clearly communicated to the team.

The airway trolley is placed outside of the room so that all potential and necessary airway equipment is quickly available. This includes supraglottic airway devices, such as laryngeal mask airways and esophageal tracheal double-lumen airways. The on-call EMT tracheostomy team should also be contactable and the telephone number known.

The connecting ports of the prepared ventilator are tested. An HME filter is connected between the Y-piece and the respiratory mask. The patient is informed of the anesthesia and intubation procedure in order to attain informed consent.

Complete vital sign monitoring is to be carried out and the ECG tone switched on. The working environment must be optimized. Ensure enough space is around the bed. The pillow is removed, and the patient positioned in a head-up position. The suction system must be fully functional with the suction catheter attached and in reaching distance of the intubating doctor. The patient should have a minimal of two intravenous cannulas, which are tested prior to intubation.

Before beginning the procedure, the team must follow a 10 second for 10 minute principle where facts, procedural planning, potential complications, and team roles are clarified and outstanding questions can be answered. The second doctor also reads and ensures that the recommendations in the airway protection checklist in COVID-19 patients is sufficiently completed. The procedure may begin once everything is clarified.

The oxygen supply to the nasal cannula is turned off. The patient’s protective mask then removed. The respiratory mask is placed and held directly on the patient’s mouth and nose with a C-grip technique. As soon as the mask is airtight, oxygen is provided through the nasal cannula at a flow rate of 3 liters per minute. The ventilator is set to a CPAP mode without pressure support and with a PEEP of 5 and FI02 of 1. The patient should be pre-oxygenated for a total of three to five minutes.

Meanwhile, the patient’s cardiovascular state is monitored, and if required, catecholamine therapy initiated. Now, the five minutes are over. In the context of a rapid sequence induction, all anesthetic agents are rapidly applied. The purpose is to achieve a rapid and deep state of anesthesia without eliciting a cough reflex or hiccup. There will be a 45-second pause after the application of muscle relaxants.

The oxygen supply over the nasal cannula is stopped. However, the nasal cannula is left in place. The ventilator is also paused. The respiratory mask is either hung to the side or placed in a kidney dish next to the patient’s head and held by the assistant positioned near the ventilator. Intubation will now be attempted through videolaryngoscopy and with an endotracheal tube with a pre-positioned bougie within. It is important to maintain as much distance as possible between the intubating doctor and the patient.

After the removal of the bougie, the endotracheal tube cuff must be blocked quickly to prevent aerosolization. The assistant detaches the respiratory mask from the breathing circuit, and places this, in turn, in a kidney dish. A closed suction system is attached to the breathing circuit and once any leaks are eliminated, ventilation can be continued.

The tube position is confirmed through capnography and auscultation. Contamination can be minimized by having a dedicated stethoscope for each patient, which is left by the patient’s bed. Now, the nasal cannula are cut and removed. The endotracheal tube is then fixed. The first pair of gloves are removed and disposed of.

Now, a nasogastric tube should be inserted and its position checked and then fixed. Per the procedures, difficult airway algorithms are well established and are also relevant in COVID-19 patients. The airway or emergency trolley is pre-prepared with all potentially necessary equipment and is placed outside of the patient room.

An allocated runner is made available to pass any equipment on to the intubated team. Supraglottic airways, such as a laryngeal tube should be utilized early on in the algorithm. This is because the potential for leakage or aerosolization of respiratory tract droplets is lower than when compared to bag mask ventilation through a normal respiratory mask. If a second intubation attempt is required, then cricothyroid pressure can be applied. If a further attempt is required, then the second doctor from the team may carry this out.

Early consideration of the need for additional personnel or technical assistance is important as donning of personal protection equipment requires significant time. If a surgical airway is necessary, such as an emergency tracheotomy, then EMT colleagues must be informed early on. Extubation should be carried out by a team of two individuals with full personal protection equipment.

The first person stands next to the ventilator. The second loosens the endotracheal tube fixation tape and operates the closed suction system. The patient is ventilated with an FI02 of 1.0 prior to extubation and with a PEEP of 5. The ventilator is placed on standby immediately prior to extubation. The patient must then be continuously suctioned whilst the endotracheal tube is carefully removed.

The breathing system may not at any point be disconnected. A tight-fitting respiratory mask is placed on the patient covering the mouth and nose, and all vital signs with particular attention to the respiratory function must be monitored.

Thank you.

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JoVE Science Education Database. JoVE Science Education. COVID-19 / Coronavirus Outbreak: Protecting The Airway – Endotracheal Intubation. JoVE, Cambridge, MA, (2020).