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Journal
/
Neuroscience
/
多孔微电极阵列中人
体外
神经培养物的聚焦超声神经调控
JoVE Journal
Neuroscience
This content is Free Access.
JoVE Journal
Neuroscience
Focused Ultrasound Neuromodulation of Human
In Vitro
Neural Cultures in Multi-Well Microelectrode Arrays
Please note that all translations are automatically generated.
Click here for the English version.
多孔微电极阵列中人
体外
神经培养物的聚焦超声神经调控
DOI:
10.3791/65115-v
•
04:00 min
•
May 03, 2024
•
Ruixing Liang
2
,
Griffin Mess
3
,
Joshua Punnoose
3
,
Kelley M. Kempski Leadingham
3
,
Constantin Smit
3
,
Nitish Thakor
4
,
Christa W. Habela
,
Betty Tyler
,
Yousef Salimpour
,
Amir Manbachi
2,3,4,5,6
1
Electrical and Computer Engineering
,
Johns Hopkins University
,
2
HEPIUS Innovation Laboratory
,
Johns Hopkins University School of Medicine
,
3
Neurosurgery
,
Johns Hopkins University School of Medicine
,
4
Biomedical Engineering
,
Johns Hopkins University School of Medicine
,
5
Mechanical Engineering
,
Johns Hopkins University
,
6
Anesthesiology and Critical Care Medicine
,
Johns Hopkins University School of Medicine
Chapters
00:00
Introduction
00:37
Preparation of Materials and Setting Up the Experiment
01:23
Stimulation and Neuronal Signal Acquisition
02:18
Results: The Neuromodulatory Effects of Focused Ultrasound (FUS) on Neurons
03:07
Conclusion
Summary
Automatic Translation
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Automatic Translation
在这里,我们提出了一种使用高通量系统的方案,该系统能够监测和量化聚焦超声对人类诱导的多能干细胞(HiPSC)神经元的神经调节作用。
Tags
Focused Ultrasound
Neuromodulation
Neural Cultures
Microelectrode Arrays
HIPSCs
Neuronal Activity
Firing Rate
FUS Parameters
In Vitro Testing
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