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Chapters
- 00:05Title
- 01:01Cell Implantation
- 03:19Preparing MB49 Cells and Implantation
- 05:00Intravesical Delivery of Adenovirus
- 06:27Representative Bladder Cancer Initiation Results
- 07:28Conclusion
Implantation of cancer cells into the organ of origin can serve as a useful preclinical model to evaluate novel therapies. MB49 bladder carcinoma cells can be grown within the bladder following intravesical instillation. This protocol demonstrates catheterization of the mouse bladder for the purpose of tumor implantation and adenoviral delivery.
