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Characterization of Metabolic Status in Nonhuman Primates with the Intravenous Glucose Tolerance Test
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Characterization of Metabolic Status in Nonhuman Primates with the Intravenous Glucose Tolerance Test

Characterization of Metabolic Status in Nonhuman Primates with the Intravenous Glucose Tolerance Test

DOI:
10.3791/52895-v

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06:59 min

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November 13, 2016

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, , , ,
1Cardiovascular and Metabolism Group,Crown Bioscience

Chapters

  • 00:05Title
  • 00:45Animal Preparation
  • 02:44Intravenous Glucose Tolerance Test (IVGTT) Procedure
  • 04:38Results: Representative IVGTT Glucose Clearance and Insulin Production Curves for Diabetic and Healthy Control Animals
  • 06:17Conclusion

Summary

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Automatic Translation

The goal of this protocol is to present a standard method to perform intravenous glucose tolerance tests (IVGTTs) to assess glycemic control in nonhuman primates and assess their metabolic status from healthy to dysmetabolic.

Tags

Intravenous Glucose Tolerance TestIVGTTMacaquesMetabolic DiseaseInsulin ResistanceDiabetesBlood GlucoseBlood SamplingDextrose InfusionSedated AnimalPulse OximeterRespiratory RateBody TemperatureCatheter PlacementHeparin-saline FlushFasting Blood GlucoseSerum SampleComplete Blood Cell Count

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