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Repeated Measurement of Respiratory Muscle Activity and Ventilation in Mouse Models of Neuromuscular Disease
JoVE Journal
Medicine
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JoVE Journal Medicine
Repeated Measurement of Respiratory Muscle Activity and Ventilation in Mouse Models of Neuromuscular Disease
DOI:

09:24 min

April 17, 2017

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Chapters

  • 00:05Title
  • 00:48Preparation for Surgery
  • 02:24Implanting the Telemetry Device to Record Scalene and Trapezius EMG Activity
  • 07:01Acquiring Simultaneous Electromyography and Plethysmography Signals
  • 08:00Results: Representative Whole-body Plethysmography (WBP) and Electromyography Traces
  • 08:56Conclusion

Summary

Automatic Translation

This paper introduces a method for repeated measurements of ventilation and respiratory muscle activity in a freely behaving amyotrophic lateral sclerosis (ALS) mouse model throughout disease progression with whole-body plethysmography and electromyography via an implanted telemetry device.

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