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Journal / Genetics / Højopløsnings smeltende PCR til…
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Genetics

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JoVE Journal Genetics
Højopløsnings smeltende PCR til komplementreceptor 1 Længde polymorfisme Genotyping
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Højopløsnings smeltende PCR til komplementreceptor 1 Længde polymorfisme Genotyping: Et innovativt redskab til Alzheimers sygdomssensibilitetsvurdering

Article DOI: 10.3791/56012-v • 07:26 min • July 18th, 2017
July 18th, 2017 •
1,2, 1,2, 1,2, 1,2, 3,4
1Department of Immunology, Reims University Hospitals, Robert Debré Hospital, 2Faculty of Medicine, LRN EA 4682, University of Reims Champagne-Ardenne, 3Department of Internal Medicine and Geriatrics, Reims University Hospitals, Maison Blanche Hospital, 4Faculty of Medicine, EA 3797, University of Reims Champagne-Ardenne

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Her beskriver vi en nyskabende metode til bestemmelse af komplementreceptor 1 (CR1) -længdepolymorfier til anvendelse i flere anvendelser, især vurderingen af ​​modtagelighed for sygdomme som Alzheimers sygdom (AD). Denne metode kan være nyttig til bedre at forstå rollen af ​​CR1-isoformer i AD-patogenesen.

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Genetik udgave 125 CR1 CD35 komplement C3b / C4b receptor CR1 længde polymorfisme komplement Alzheimers sygdom molekylærbiologi neurovidenskab systemisk lupus erythematosus genetisk risiko
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