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A Standardized Method for Measuring Internal Lung Surface Area via Mouse Pneumonectomy and Prosthesis Implantation
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Chapters
- 00:05Title
- 00:46Mouse Pnemonectomy (PNX) Surgery
- 03:28Mouse Lung Prosthesis Implantation
- 04:17Measurement of Internal Lung Volume (ILV)
- 06:17Measurement of Mean Linear Intercept (MLI) of Lung Accessory Lobes
- 07:14Results: Lung Surface Area After Prosthesis Implantation
- 08:19Conclusion
Internal lung surface area (ISA) is a critical criterion for assessing lung morphology and physiology in lung diseases and injury-induced alveolar regeneration. We describe here a standardized method that can minimize the measurement bias for ISA in both lung pneumonectomy and prosthesis implantation mouse models.
