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Imaging Integrin Tension and Cellular Force at Submicron Resolution with an Integrative Tension Sensor
JoVE Journal
Bioengineering
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JoVE Journal Bioengineering
Imaging Integrin Tension and Cellular Force at Submicron Resolution with an Integrative Tension Sensor
DOI:

07:20 min

April 25, 2019

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Chapters

  • 00:04Title
  • 00:36Integrative Tension Sensor Synthesis
  • 02:58Integrative Tensor Sensor (ITS) Immobilization
  • 03:58Cell Plating
  • 05:14Quasi-real Time Live Cell Integrin Tension Imaging
  • 06:05Results: Representative ITS Imaging
  • 06:52Conclusion

Summary

Automatic Translation

Integrin tension plays important roles in various cell functions. With an integrative tension sensor, integrin tension is calibrated with picoNewton (pN) sensitivity and imaged at submicron resolution.

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