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Journal / Immunology and Infection / Inducerande Meningokockmeningit serogrupp C hos…
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Immunology and Infection

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JoVE Journal Immunology and Infection
Inducerande Meningokockmeningit serogrupp C hos möss via Intracisternal förlossning
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Inducerande Meningokockmeningit serogrupp C hos möss via Intracisternal förlossning

Article DOI: 10.3791/60047-v • 10:03 min • November 5th, 2019
November 5th, 2019 •
1, 1, 1, 1, 1, 1, 2, 1, 1,3
1Department of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, 2Department of Science and Technology, Sannio University, 3CEINGE – Advanced Biotechnology

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Här beskriver vi en metod för att inducera meningokockmeningit genom en intracisternal infektionsväg hos vuxna möss. Vi presenterar ett steg för steg-protokoll för meningokockinfektion från beredningen av inokulum till intracisternal infektion; registrera sedan djurens överlevnad och utvärdera bakterie laster i murina vävnader.

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Immunologi och infektion fråga 153 infektion Neisseria meningitidis meningokockmeningit musmodeller intracisternal injektion hjärnvävnad ISOGEN Mutant stam.
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