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Journal / Medicine / 经过验证的LC-MS/MS面板，用于在小头发样本中量化11种耐药结核病药物…
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经过验证的LC-MS/MS面板，用于在小头发样本中量化11种耐药结核病药物
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经过验证的LC-MS/MS面板，用于在小头发样本中量化11种耐药结核病药物

Article DOI: 10.3791/60861-v • 08:54 min • May 19th, 2020
May 19th, 2020 •
1, 1, 1, 2, 3, 4, 1
1Department of Obstetrics, Gynecology and Reproductive Sciences, TB Hair Analysis Laboratory, University of California San Francisco, 2Department of Epidemiology and Biostatistics, University of California San Francisco, 3Department of Medicine, Division of HIV, Infectious Diseases, and Global Medicine, University of California San Francisco, 4Department of Medicine, Division of Pulmonary and Critical Care Medicine, University of California San Francisco

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目前分析患者是否遵守复杂耐药结核病（DR-TB）方案的方法可能不准确且资源密集。我们的方法分析头发，一个易于收集和储存的基质，浓度为11个DR-TB药物。使用LC-MS/MS，我们可以确定亚纳米格药物水平，可用于更好地了解药物依从性。

Tags

医学， 问题 159， LC-MS/MS， 耐多药结核病药物， 头发分析， 坚持监测， 治疗药物监测， 耐药结核病
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