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Genetics

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JoVE Journal Genetics
CRISPR/Cas9 Gene edição para fazer condicional mutantes de humano parasita da malária por p. falciparum
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CRISPR/Cas9 Gene edição para fazer condicional mutantes de humano parasita da malária por p. falciparum

Article DOI: 10.3791/57747-v • 09:25 min • September 18th, 2018
September 18th, 2018 •
*1,2, *1, 1,2, 1, 1,2
1Department of Cellular Biology, University of Georgia, 2Center for Tropical and Emerging Global Diseases, University of Georgia
* These authors contributed equally

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Nós descrevemos um método para gerar MLG-baseado condicionais "knockdown" mutantes do Plasmodium falciparum usando CRISPR/Cas9 edição do genoma.

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Genética edição 139 CRISPR Plasmodium MLG nocaute malária genética
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