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Immunology and Infection

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JoVE Journal Immunology and Infection
Intraperitoneal glukose Tolerance Test, måling af lungefunktion og fiksering af lungerne at studere virkningerne af fedme og hæmmet metabolisme på pulmonal resultater
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Intraperitoneal glukose Tolerance Test, måling af lungefunktion og fiksering af lungerne at studere virkningerne af fedme og hæmmet metabolisme på pulmonal resultater

Article DOI: 10.3791/56685-v • 08:30 min • March 15th, 2018
March 15th, 2018 •
1, 1, 1,2, 1, 2, 3, 2, 1,2
1Translational Experimental Pediatrics, Experimental Pulmonology, Department of Pediatrics and Adolescent Medicine, University of Cologne, 2Department of Pediatrics and Adolescent Medicine, University of Cologne, 3Division of Experimental Pediatrics and Metabolism, University Children's Hospital, Heinrich Heine University Düsseldorf

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Forekomsten af fedme er stigende og øger risikoen for kroniske lungesygdomme. For at fastsætte de underliggende mekanismer og forebyggende strategier, veldefinerede dyre modeller er nødvendige. Her give vi tre metoder (glucose-tolerance-test, krop plethysmography og lunge fiksering) at studere effekten af fedme på pulmonal resultater i mus.

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Immunologi og infektion sag 133 glukose Tolerance Test lungefunktion lunge fiksering fedme luftvejene modstand dynamisk overholdelse kronisk lungesygdom
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