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Neuroscience

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Génération simple d’une Culture de haut rendement de neurones induits des fibroblastes de la peau humaine adulte

Article DOI: 10.3791/56904-v • 09:07 min • February 5th, 2018
February 5th, 2018 •
1, 1, 1,2, 1, 1
1Department of Experimental Medical Science, Wallenberg Neuroscience Center, Division of Neurobiology and Lund Stem Cell Center, Lund University, 2John van Geest Centre for Brain Repair & Department of Neurology, Department of Clinical Neurosciences and Cambridge Stem Cell Institute, University of Cambridge

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Reprogrammation neuronale directe génère des neurones qui maintiennent l’âge de la cellule somatique départ. Nous décrivons ici une méthode basée sur un vecteur unique pour générer des neurones induites de fibroblastes dermiques provenant de donneurs humains adultes.

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Neurosciences numéro 132 Induced neurones des fibroblastes dermiques humains adultes directement la reprogrammation neurones les neurones humains purification de FACS vecteur lentiviral
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