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Enkla Generation av en hög avkastning kultur av inducerade nervceller från mänsklig vuxen hud fibroblaster

Article DOI: 10.3791/56904-v • 09:07 min • February 5th, 2018
February 5th, 2018 •
1, 1, 1,2, 1, 1
1Department of Experimental Medical Science, Wallenberg Neuroscience Center, Division of Neurobiology and Lund Stem Cell Center, Lund University, 2John van Geest Centre for Brain Repair & Department of Neurology, Department of Clinical Neurosciences and Cambridge Stem Cell Institute, University of Cambridge

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Direkta neuronala omprogrammering genererar nervceller som upprätthåller en ålder av somatiska startcellen. Här beskriver vi en enda vektor-baserade metod för att generera inducerade nervceller från dermal fibroblaster från vuxen människa givare.

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Neurovetenskap fråga 132 inducerad nervceller vuxen mänskliga dermal fibroblaster direkt neurala omprogrammering mänskliga nervceller FACS rening lentiviral vektor
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