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Sencilla generación de una cultura de alto rendimiento de las neuronas inducidas de fibroblastos de piel humana adulta

Article DOI: 10.3791/56904-v • 09:07 min • February 5th, 2018
February 5th, 2018 •
1, 1, 1,2, 1, 1
1Department of Experimental Medical Science, Wallenberg Neuroscience Center, Division of Neurobiology and Lund Stem Cell Center, Lund University, 2John van Geest Centre for Brain Repair & Department of Neurology, Department of Clinical Neurosciences and Cambridge Stem Cell Institute, University of Cambridge

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Reprogramación neuronal directa genera neuronas que mantienen la edad de la partida de la célula somática. Aquí, describimos un método único basado en vectores para generar neuronas inducidas de fibroblastos dérmicos obtenidos de donantes humanos adultos.

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Neurociencias número 132 inducido las neuronas fibroblastos dérmicos humanos adultos dirigen reprogramación neural las neuronas humanas purificación de FACS vectores lentivirales
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