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Journal / Cancer Research / 同系小鼠原位同种异体移植物模拟胰腺癌…
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同系小鼠原位同种异体移植物模拟胰腺癌
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同系小鼠原位同种异体移植物模拟胰腺癌

Article DOI: 10.3791/64253-v • 06:20 min • October 4th, 2022
October 4th, 2022 •
1,2,3, 1,2,3,4, *1,2,3, *1,2,3
1Division of Translational Cancer Research, German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), 2Translational Cancer Research and Institute of Experimental Cancer Therapy, Klinikum rechts der Isar, School of Medicine, Technical University of Munich, 3Center for Translational Cancer Research (TranslaTUM), School of Medicine, Technical University of Munich, 4Department of Internal Medicine II, Klinikum rechts der Isar, Technical University of Munich
* These authors contributed equally

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胰腺导管腺癌 （PDAC） 的同源小鼠原位同种异体移植物概括了疾病亚型的生物学、表型和治疗反应。由于其快速、可重复的肿瘤进展，它们被广泛用于临床前研究。在这里，我们展示了生成这些模型的常见做法，将同源鼠PDAC培养物注射到胰腺中。

Tags

癌症研究，第188期，胰腺，原位植入，同种异体移植，胰腺导管腺癌，肿瘤微环境，治疗
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