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Journal / Cancer Research / 膵臓癌モデルへの同系マウス同所性同種移植片…
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JoVE Journal Cancer Research
膵臓癌モデルへの同系マウス同所性同種移植片
Pathological Analysis of Lung Metastasis Following Lateral Tail-Vein Injection of Tumor Cells
Journal (Cancer Research)
Pathological Analysis of Lung Metastasis Following Lateral Tail-Vein Injection of Tumor Cells
Automated Multiplex Immunofluorescence Panel for Immuno-oncology Studies on Formalin-fixed Carcinoma Tissue Specimens
Journal (Cancer Research)
Automated Multiplex Immunofluorescence Panel for Immuno-oncology Studies on Formalin-fixed Carcinoma Tissue Specimens
 
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膵臓癌モデルへの同系マウス同所性同種移植片

Article DOI: 10.3791/64253-v • 06:20 min • October 4th, 2022
October 4th, 2022 •
1,2,3, 1,2,3,4, *1,2,3, *1,2,3
1Division of Translational Cancer Research, German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), 2Translational Cancer Research and Institute of Experimental Cancer Therapy, Klinikum rechts der Isar, School of Medicine, Technical University of Munich, 3Center for Translational Cancer Research (TranslaTUM), School of Medicine, Technical University of Munich, 4Department of Internal Medicine II, Klinikum rechts der Isar, Technical University of Munich
* These authors contributed equally

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膵管腺癌(PDAC)の同系マウス同所性同種移植片は、疾患サブタイプの生物学、表現型、および治療反応を再現します。迅速で再現性のある腫瘍進行により、前臨床試験で広く使用されています。ここでは、これらのモデルを生成するための一般的な方法を示し、同系マウスPDAC培養物を膵臓に注入します。

Tags

がん研究、第188号、膵臓、同所移植、同種移植、膵管腺癌、腫瘍微小環境、治療
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