A subscription to JoVE is required to view this content. Sign in or start your free trial.
1Department of Orthopaedic Sports Medicine,Klinikum rechts der Isar der Technischen Universität München, 2Department of Radiology,Klinikum rechts der Isar der Technischen Universität München, 3Institute of Experimental Oncology and Therapy Research,Klinikum rechts der Isar der Technischen Universität München, 4Department of Radiology,Uniklinik Köln
Chapters
- 00:05Title
- 01:31Cartilage Biopsy
- 03:01In vitro Culture
- 05:01Cell-seeding of the Matrix
- 06:09Matrix-assisted Autologous Chondrocyte Transplantation
- 07:26Results: Successful Isolation and Implantation of Autologous Chondrocytes into an Artificial Chondral Defect
- 08:12Conclusion
An experimental technique for the treatment of chondral defects in the rabbit's knee joint is described. The implantation of autologous chondrocytes seeded on a matrix is a well-accepted method for the remodeling and repair of articular cartilage lesions providing satisfying long-term results. Matrix-assisted autologous chondrocyte transplantation (MACT) offers a standardized and clinically established implantation method.
Tags
Matrix-assisted Autologous Chondrocyte TransplantationChondral DefectsRabbit ModelArticular CartilageSelf-regenerationCartilage LesionsSurgical TechniquesHyaline Articular CartilageLong-term RecoveryRegenerative TechniquesChondrogenic PotentialTransplanted CellsRegenerative Cartilage TherapiesAutologous Chondrocyte Implantation (ACI)Large Hyaline Cartilage Defects
