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Journal / Neuroscience / Un metodo per High Fidelity optogenetic controllo …
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Neuroscience

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JoVE Journal Neuroscience
Un metodo per High Fidelity optogenetic controllo dei singoli Piramidale neuroni
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Un metodo per High Fidelity optogenetic controllo dei singoli Piramidale neuroni

Article DOI: 10.3791/50291 • 13:44 min
September 2nd, 2013 •
*1,2, *1,2, 1,2
1Institute for Behavioral Genetics, University of Colorado Boulder, 2Department of Psychology and Neuroscience, University of Colorado Boulder
* These authors contributed equally

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September 2nd, 2013

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Il recente sviluppo di strumenti neuroscienza che combinano genetica e ottica, definito "optogenetics", consente il controllo sulle attività del circuito neurale con un livello senza precedenti di risoluzione spaziale e temporale. Qui forniamo un protocollo per l'integrazione nella registrazione vivo con la manipolazione optogenetic di sottoinsiemi geneticamente definiti di neuroni piramidali corticali prefrontali e subicular.

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