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Journal / Neuroscience / Um Método para High Fidelity Optogenetic Controle …
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Neuroscience

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JoVE Journal Neuroscience
Um Método para High Fidelity Optogenetic Controle de Individual Piramidal neurônios
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Um Método para High Fidelity Optogenetic Controle de Individual Piramidal neurônios

Article DOI: 10.3791/50291 • 13:44 min
September 2nd, 2013 •
*1,2, *1,2, 1,2
1Institute for Behavioral Genetics, University of Colorado Boulder, 2Department of Psychology and Neuroscience, University of Colorado Boulder
* These authors contributed equally

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September 2nd, 2013

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O recente desenvolvimento de ferramentas de neurociência que combinam genética e óptica, denominado "optogenetics", possibilita o controle sobre a atividade do circuito neural com um nível sem precedentes de resolução espacial e temporal. Aqui nós fornecemos um protocolo para a integração na gravação vivo com manipulação optogenetic de subconjuntos geneticamente definidos de neurônios piramidais corticais pré-frontais e subicular.

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