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生物荧光原位模型胰腺癌进展
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JoVE Journal Medicine
Bioluminescent Orthotopic Model of Pancreatic Cancer Progression
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生物荧光原位模型胰腺癌进展

DOI:
10.3791/50395-v

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09:25 min

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June 28, 2013

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, , ,
1Monash Institute of Pharmaceutical Sciences,Monash University, 2Department of Visceral Surgery and Medicine,University of Bern, 3Cousins Center for Neuroimmunology,University of California Los Angeles

Chapters

  • 00:05Title
  • 01:46Pancreatic Cancer Cell Preparation
  • 02:59Mouse Preparation
  • 03:45Laparotomy
  • 06:18Bioluminescent Tracking of Pancreatic Cancer Progression
  • 07:33Results: Bioluminescent Imaging, Growth Kinetics, and Histological Analysis of Orthotopic Pancreatic Tumors
  • 08:58Conclusion

Summary

Automatic Translation

Automatic Translation

改进胰腺癌生物学的理解是迫切需要的，以便更好的治疗选择治疗胰腺癌的发展。为了满足这一需求，我们展示了胰脏癌，原位模型允许非侵入性的监测癌症进展<em>在体内</em>生物发光成像。

Tags

BioluminescentOrthotopicPancreatic CancerProgressionIn Vivo ImagingLuciferaseMatrigelPrimary TumorMetastasisSyngeneicXenograftPre-clinical TrialsAnti-cancer Therapeutics

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