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Fremme af overlevelse og differentiering af neurale stamceller med fibrin og Growth Factor Cocktails efter Svær Rygmarvsskader
JoVE Journal
Neuroscience
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JoVE Journal Neuroscience
Promotion of Survival and Differentiation of Neural Stem Cells with Fibrin and Growth Factor Cocktails after Severe Spinal Cord Injury
DOI:

09:56 min

July 27, 2014

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Chapters

  • 00:05Title
  • 01:51T3 Spinal Cord Transection
  • 04:25Preparation of Spinal Cord Neural Stem Cells
  • 06:22Transplantation of Cells into Spinal Cord Lesion
  • 07:29Results: Grafted Cell Survival and Morphology
  • 09:31Conclusion

Summary

Automatic Translation

Fibrin matricer indeholdende vækstfaktorer blev brugt til at tilbageholde påhæftede neurale stamceller i lokaliteter af komplette rygmarv transection. Transplanterede celler helt fyldt læsionen hulrum og differentieres i flere neurale celletyper, herunder neuroner, der udvidede axoner i værtscelle rygmarven over lange afstande.

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