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血管再生在中枢神经系统中使用的小鼠视网膜评估
JoVE Journal
Neuroscience
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JoVE Journal Neuroscience
Assessment of Vascular Regeneration in the CNS Using the Mouse Retina
DOI:

07:32 min

June 23, 2014

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Chapters

  • 00:05Title
  • 01:52Oxygen Induced Retinopathy (OIR) and Intravitreal Injection
  • 02:51Assessment of Vessel Perfusion and Barrier Function by Fluorescein Angiography
  • 03:29Enucleation and Eye Fixation
  • 04:16Retinal Dissection
  • 05:11Retinal Vascular Staining
  • 06:13Results: Vascular Regeneration in the Mouse Retina
  • 06:46Conclusion

Summary

Automatic Translation

啮齿动物视网膜长期以来被认为是可访问的窗口到大脑。在此技术论文中,我们提供了一个协议,它采用的氧诱导视网膜病变研究,导致血管再生的失败缺血性损伤后的中枢神经系统内的机制的小鼠模型。所描述的系统也可以利用,以探讨策略,视网膜和中枢神经系统内促进功能性血管再生。

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