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1Orthopaedic Hospital Research Center, Orthopaedic Hospital Department of Orthopaedic Surgery,David Geffen School of Medicine at University of California, Los Angeles (UCLA), 2PerkinElmer, 3Department of Dermatology,Johns Hopkins University School of Medicine, 4Department of Medicine, Division of Infectious Diseases, Department of Orthopaedic Surgery,Johns Hopkins University School of Medicine
Chapters
- 00:05Title
- 01:51Mouse Surgical Procedure
- 03:562D Optical Imaging (In vivo Bioluminescent and Fluorescent Imaging)
- 06:35µCT Image Acquisition
- 08:113D Optical Image Acquisition, Formation and µCT Co-registration
- 12:18µCT Image Analysis
- 16:09Results: Representative Bioluminescent and µCT Images
- 17:49Conclusion
Kombineret optisk og μCT billeddannelse i en musemodel af ortopædisk implantat infektion ved anvendelse af en bioluminescerende manipuleret stamme af Staphylococcus aureus, forudsat at evnen til ikke-invasivt og i længderetningen overvåge dynamik bakteriel infektion, såvel som den tilsvarende inflammatoriske respons og anatomiske ændringer i knogle.
