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血管球囊损伤和腔内管理在大鼠颈动脉
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Medicine
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JoVE Journal
Medicine
Vascular Balloon Injury and Intraluminal Administration in Rat Carotid Artery
Please note that all translations are automatically generated.
Click here for the English version.
血管球囊损伤和腔内管理在大鼠颈动脉
DOI:
10.3791/52045-v
•
09:41 min
•
December 23, 2014
•
Wei Zhang
,
Mohamed Trebak
1
Nanobioscience
,
State University of New York College of Nanoscale Science and Engineering (SUNY CNSE)
Chapters
00:05
Title
01:28
Preparations
02:30
Isolating the Common Carotid Artery (CCA)
03:29
The Balloon Injury
05:29
Intraluminal Administration of Reagents
06:43
Closing the Wound and Pre-operative Care
07:43
Results: Neoitima Formation with Vessel Injury
08:58
Conclusion
Summary
Automatic Translation
English (Original)
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Automatic Translation
该协议使用球囊导管引起的大鼠颈动脉腔内损伤,从此引起内膜增生。这是一个公认的模型用于研究在响应损伤的血管重塑的机制。它也被广泛使用,以确定潜在的治疗方法的有效性。
Tags
Vascular Balloon Injury
Rat Carotid Artery
Neointima Formation
Vascular Remodeling
Gene Transfer
ShRNA Transfer
Vascular Smooth Muscle Cells
Cell Signaling Pathways
Histological Analysis
Immunohistochemistry
Protein/mRNA Assays
Activity Assays
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