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Remote Limb Ischemic Preconditioning: A Neuroprotective Technique in Rodents
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Remote Limb Ischemic Preconditioning: A Neuroprotective Technique in Rodents

Remote Limb Ischemic Preconditioning: A Neuroprotective Technique in Rodents

DOI:
10.3791/52213-v

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07:52 min

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June 02, 2015

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1Discipline of Physiology and Bosch Institute, Sydney Medical School,University of Sydney

Chapters

  • 00:05Title
  • 01:19Equipment Preparation and Calibration of Sphygmomanometer
  • 02:33Animal Preparation and Application of Skin Temperature Probe
  • 03:55Remove Ischemia
  • 05:42Results: Remote Ischemic Preconditioning
  • 07:19Conclusion

Summary

Automatic Translation

Automatic Translation

Remote ischemic preconditioning (RIP) is a method of conditioning tissues against damaging stress. We have established a method of remote ischemia at the hind limb, by inflating a sphygmomanometer cuff for 5-10 min. The neuroprotective capabilities of RIP have been demonstrated in a model of retinal degeneration in rodents.

Tags

Keywords: Remote Limb Ischemic PreconditioningNeuroprotectionRodentsSublethal IschemiaIschemic PreconditioningRemote Ischemic PreconditioningIschemic LimbRetinal ProtectionBright Light-induced Retinal Damage

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