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JoVE Journal
Immunology and Infection

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Mouse Naïve CD4+ T Cell Isolation and In vitro Differentiation into T Cell Subsets
 

Mouse Naïve CD4+ T Cell Isolation and In vitro Differentiation into T Cell Subsets

Article DOI: 10.3791/52739
April 16th, 2015

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Summary April 16th, 2015

Naïve CD4+ T cells polarize to various subsets depending on the environment at the time of activation. The differentiation of naïve CD4+ T cells to various effector subsets can be achieved in vitro through the addition of T cell receptor stimuli and specific cytokine signals.

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