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Bioengineering
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定制设计的基于激光的加热装置顺铂触发释放的热敏脂质体与磁共振成像制导
JoVE Journal
Bioengineering
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JoVE Journal
Bioengineering
Custom-designed Laser-based Heating Apparatus for Triggered Release of Cisplatin from Thermosensitive Liposomes with Magnetic Resonance Image Guidance
Please note that all translations are automatically generated.
Click here for the English version.
定制设计的基于激光的加热装置顺铂触发释放的热敏脂质体与磁共振成像制导
DOI:
10.3791/53055-v
•
07:47 min
•
December 13, 2015
•
Yannan N. Dou
,
Robert A. Weersink
5
,
Warren D. Foltz
6
,
Jinzi Zheng
6
,
Naz Chaudary
,
David A. Jaffray
3,4,5,6
,
Christine Allen
1
Leslie Dan Faculty of Pharmacy
,
University of Toronto
,
2
Department of Radiation Oncology
,
University of Toronto
,
3
Medical Biophysics
,
University of Toronto
,
4
Institute of Biomaterials & Biomedical Engineering
,
University of Toronto
,
5
Techna Institute and Radiation Medicine Program, Princess Margaret Cancer Center
,
University Health Network
,
6
STTARR Innovation Center
,
University Health Network
,
7
Ontario Cancer Institute
,
University Health Network
Chapters
00:05
Title
02:00
Liposome Preparation
03:42
Subcutaneous Cervical Tumor Xenograft Implantation
05:08
Conformal Tumor Heating via Custom Laser Chamber
06:15
Results: Representative Tumor Laser Treatment Analyses
07:12
Conclusion
Summary
Automatic Translation
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Automatic Translation
的MRI兼容的定制设计的基于激光的加热装置已经开发出来,提供以激活从热敏脂质体释放剂特别在肿瘤区域皮下肿瘤的局部加热。
Tags
Thermosensitive Liposomes
Cisplatin
Laser-based Heating
MR Thermometry
Drug Delivery
Tumor Targeting
EPR Effect
Triggered Drug Release
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