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Preclinical Model of Hind Limb Ischemia in Diabetic Rabbits
 

Preclinical Model of Hind Limb Ischemia in Diabetic Rabbits

Article doi: 10.3791/58964
June 2nd, 2019

Summary June 2nd, 2019

We describe a surgical procedure used to induce peripheral ischemia in rabbits with hyperlipidemia and diabetes. This surgery acts as a preclinical model for conditions experienced in peripheral artery disease in patients. Angiography is also described as a means to measure the extent of introduced ischemia and recovery of perfusion.

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