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使用多氟化胆汁酸和<em>在体内</em>磁共振成像来衡量胆汁酸运输
JoVE Journal
Medicine
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JoVE Journal Medicine
Using Multi-fluorinated Bile Acids and In Vivo Magnetic Resonance Imaging to Measure Bile Acid Transport
DOI:

08:42 min

November 27, 2016

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Chapters

  • 00:05Title
  • 00:5919F-Labeled Bile Acid Gavage, Organ Harvest and Bile Acid Measurement
  • 04:02Live Animal Proton (1H) and Fluorine (19F) Magnetic Resonance Imaging (MRI)
  • 05:51Results: Representative Multi-fluorinated Bile Acid (MFBA) Measurement in the Mouse Gallbladder
  • 07:51Conclusion

Summary

Automatic Translation

工具来诊断胆汁酸的吸收不良,并测量在体内胆汁酸转运的限制。活体动物一个创新的方法,描述了利用质子结合(1小时)加氟(19 F)磁共振成像;这种新颖的方法具有平移潜力筛选在临床实践中的胆汁酸吸收不良。

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