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1Elemental Bio-imaging Facility,University of Technology Sydney, 2Florey Institute of Neuroscience and Mental Health,The University of Melbourne, 3Department of Pathology,The University of Melbourne, 4School of Earth Sciences,The University of Melbourne, 5Research School,Ruhr University, 6Department of Physiology,Monash University, 7ESI Ltd., Bozeman, 8Agilent Technologies, Mulgrave
Chapters
- 00:05Title
- 01:12Preparation of the Laser Ablation – Inductively Coupled Plasma – Mass Spectrometry (LA-ICP-MS)
- 03:57LA-ICP-MS Data Acquisition and Analysis
- 06:49Results: Metal Distribution in a WT Mouse Brain
- 07:32Conclusion
Kvantitativt kortlægning metaller i væv ved hjælp af laser ablation - induktivt koblet plasma - massespektrometri (LA-ICP-MS) er en følsom analytisk teknik, der kan give ny indsigt i, hvordan metaller deltager i normale funktion og sygdomsprocesser. Her beskriver vi en protokol til kvantitativt billeddannelse metaller i tynde sektioner af mus neurologisk væv.
