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JoVE Journal
Developmental Biology

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Cell Lineage Analyses and Gene Function Studies Using Twin-spot MARCM
 

Cell Lineage Analyses and Gene Function Studies Using Twin-spot MARCM

Article doi: 10.3791/55278
March 2nd, 2017

Summary March 2nd, 2017

Here, we present a protocol for a mosaic labeling technique that permits the visualization of neurons derived from a common progenitor cell in two distinct colors. This facilitates neural lineage analysis with the capability of birth-dating individual neurons and studying gene function in the same neurons of different individuals.

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