JoVE
JoVE
Faculty Resource Center
Research
Behavior
Biochemistry
Biology
Bioengineering
Cancer Research
Chemistry
Developmental Biology
Engineering
Environment
Genetics
Immunology and Infection
Medicine
Neuroscience
JoVE Journal
JoVE Encyclopedia of Experiments
JoVE Chrome Extension
Education
Biology
Chemistry
Clinical
Engineering
Environmental Sciences
Pharmacology
Physics
Psychology
Statistics
JoVE Core
JoVE Science Education
JoVE Lab Manual
JoVE Quiz
JoVE Business
Videos Mapped to your Course
Authors
Librarians
High Schools
About
Sign-In
Sign In
Contact Us
Research
JoVE Journal
JoVE Encyclopedia of Experiments
Education
JoVE Core
JoVE Science Education
JoVE Lab Manual
High Schools
EN
EN - English
CN - 中文
DE - Deutsch
ES - Español
KR - 한국어
IT - Italiano
FR - Français
PT - Português
EN
EN - English
CN - 中文
DE - Deutsch
ES - Español
KR - 한국어
IT - Italiano
FR - Français
PT - Português
Close
Research
Behavior
Biochemistry
Bioengineering
Biology
Cancer Research
Chemistry
Developmental Biology
Engineering
Environment
Genetics
Immunology and Infection
Medicine
Neuroscience
Products
JoVE Journal
JoVE Encyclopedia of Experiments
Education
Biology
Chemistry
Clinical
Engineering
Environmental Sciences
Pharmacology
Physics
Psychology
Statistics
Products
JoVE Core
JoVE Science Education
JoVE Lab Manual
JoVE Quiz
JoVE Business
Videos Mapped to Your Course
Teacher Resources
Get in Touch
Instant Trial
Log In
EN
EN - English
CN - 中文
DE - Deutsch
ES - Español
KR - 한국어
IT - Italiano
FR - Français
PT - Português
Journal
/
Biology
/
一个协议来使用基因集富集分析以确定合适的动物模型转化型研究
JoVE Journal
Biology
A subscription to JoVE is required to view this content.
Sign in or start your free trial.
JoVE Journal
Biology
A Protocol for Using Gene Set Enrichment Analysis to Identify the Appropriate Animal Model for Translational Research
Please note that all translations are automatically generated.
Click here for the English version.
一个协议来使用基因集富集分析以确定合适的动物模型转化型研究
DOI:
10.3791/55768-v
•
09:35 min
•
August 16, 2017
•
Christopher Weidner
,
Matthias Steinfath
,
Elisa Wistorf
,
Michael Oelgeschläger
,
Marlon R. Schneider
,
Gilbert Schönfelder
2
1
Department of Experimental Toxicology and ZEBET
,
German Federal Institute for Risk Assessment (BfR)
,
2
Department of Clinical Pharmacology and Toxicology
,
Charité-Universitätsmedizin Berlin
Chapters
00:05
Title
00:54
Performing the Game Set Enrichment Analysis (GSEA)
05:46
Comparing the GSEA Results and Identifying the Optimal Animal Model
07:55
Results: Overlap of Pathway Regulation Identifies Suitable and Unsuitable Animal Models
08:49
Conclusion
Summary
Automatic Translation
English (Original)
العربية (Arabic)
中文 (Chinese)
Nederlands (Dutch)
français (French)
Deutsch (German)
עברית (Hebrew)
italiano (Italian)
日本語 (Japanese)
한국어 (Korean)
português (Portuguese)
русский (Russian)
español (Spanish)
Türkçe (Turkish)
Automatic Translation
我们提供一个标准化的协议用于基因集的浓缩转录组数据分析,找出理想的小鼠模型的转化研究。
该协议可以用 DNA 微阵列和 RNA 测序数据,并且可以进一步扩展到其他组学数据如果数据可用。
Tags
Gene Set Enrichment Analysis
Animal Model
Translational Research
Genome Data
Mouse Models
Inflammatory Diseases
Gene Expression Studies
Gene Expression Data
Phenotype File
Molecular Signature Database
DNA Chip Annotations
GSEA Software
Gene Symbols
Permutations
Article
Embed
ADD TO PLAYLIST
Usage Statistics
Related Videos
测试的速度和运动方向的视觉灵敏度在蜥蜴
计算机生成的动物模型的刺激
使用基因脉冲MXcell电穿孔系统主细胞的转染效率高
采用芯片识别亚型特定的靶基因的全基因组分析
鼠类全胚胎培养方法,使用的肩型瓶培养系统
核糖体束缚新生多肽的分离<em>在体外</em>确定沿mRNA的翻译暂停网站
作为一种工具来隔离核糖体的束缚多肽SECM逮捕序列
Using
Caenorhabditis elegans
as a Model System to Study Protein Homeostasis in a Multicellular Organism
非洲爪蟾
作为一种模型来确定翻译减值
完整的工作流程为组蛋白翻译后修饰的分析采用自下而上质谱法:从组蛋白提取数据分析
Read Article