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Behavior
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一种简便、低成本的肌营养不良小鼠步行模型的测定方法
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A Simple and Low-cost Assay for Measuring Ambulation in Mouse Models of Muscular Dystrophy
Please note that all translations are automatically generated.
Click here for the English version.
一种简便、低成本的肌营养不良小鼠步行模型的测定方法
DOI:
10.3791/56772-v
•
05:54 min
•
December 29, 2017
•
Elizabeth M. Gibbs
2
,
Rachelle H. Crosbie-Watson
2,3,4
1
Department of Integrative Biology and Physiology
,
University of California
,
2
Center for Duchenne Muscular Dystrophy
,
University of California
,
3
Department of Neurology
,
David Geffen School of Medicine, University of California
,
4
Molecular Biology Institute
,
University of California
Chapters
00:05
Title
00:43
Chamber Preparation, Muscle Activation, and Ambulation Recording
01:50
Video Analysis
03:28
Results: Analysis of
mdx
Ambulation and Representative Effects of Exercise
05:16
Conclusion
Summary
Automatic Translation
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Automatic Translation
该协议描述了一个灵活的, 低成本的测量鼠标移动在野外活动的测试系统。我们显示, 基于这个系统的6分钟的步行试验检测到在
mdx
小鼠中自愿运动的减少, 并准确地区分了这些动物的肌肉特异性抢救的改进。
Tags
Muscular Dystrophy
Mouse Model
Ambulation
Activity
Grip Strength
Video Tracking
Non-invasive
Reproducible
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