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一种简便、低成本的肌营养不良小鼠步行模型的测定方法
JoVE Journal
Behavior
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JoVE Journal Behavior
A Simple and Low-cost Assay for Measuring Ambulation in Mouse Models of Muscular Dystrophy
DOI:

05:54 min

December 29, 2017

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Chapters

  • 00:05Title
  • 00:43Chamber Preparation, Muscle Activation, and Ambulation Recording
  • 01:50Video Analysis
  • 03:28Results: Analysis of mdx Ambulation and Representative Effects of Exercise
  • 05:16Conclusion

Summary

Automatic Translation

该协议描述了一个灵活的, 低成本的测量鼠标移动在野外活动的测试系统。我们显示, 基于这个系统的6分钟的步行试验检测到在mdx小鼠中自愿运动的减少, 并准确地区分了这些动物的肌肉特异性抢救的改进。

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