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A Simple and Low-cost Assay for Measuring Ambulation in Mouse Models of Muscular Dystrophy
 

A Simple and Low-cost Assay for Measuring Ambulation in Mouse Models of Muscular Dystrophy

Article DOI: 10.3791/56772
December 29th, 2017

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Summary December 29th, 2017

This protocol describes a flexible, low-cost system for measuring mouse ambulation in an open field activity assay. We show that a 6-minute ambulation assay based on this system detects a decrease in voluntary movement in mdx mice, and accurately distinguishes improvement in a muscle-specific rescue of these animals.

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